M. M. Ismail, M. Abass, M. Hassan
Dec 18, 2000
Citations
0
Influential Citations
29
Citations
Journal
Molecules
Abstract
Mostafa M. Ismail, Mohamed Abass* and Mohamed M. HassanDepartment of Chemistry, Faculty of Education, Ain Shams University, Roxy, 11711 Cairo, Egypt.Tel: + 202 7104060, Fax: + 202 2581243. * Author to whom correspondence should be addressed; E-mail: mohamedabass@hotmail.com† For part V see reference [1].Received: 12 October 2000; in revised form: 2 November 2000 / Accepted: 9 November 2000 /Published:18 December 2000Abstract: The synthesis of 4-chloro-8-methylquinolin-2(1H)-one and its thione analogue is described. Some nucleophilic substitution reactions of the 4-chloro group were carried out to get new 4-substituted 2-quinolinones and quinolinethiones, such as 4-sulfanyl, hydrazino, azido and amino derivatives, which are of important synthetic use. The structure of the new compounds was established by their elemental analysis, IR and