C. Thomas
1953
Citations
0
Influential Citations
0
Citations
Journal
Proceedings of the Royal Society of Medicine
Abstract
the stilboestrol may upset the balance between androgens and oestrogens in the body and thus influence the growth of the new tissue. Others have suggested that the action may be due to some particular molecular configuration of the oestrogen. Dodds and his colleagues, responsible for the synthesis of the stilboestrol group of substances, have always pointed out that the structural resemblance of these substances to naturally occurring hormones is only superficial, and there would appear to be little advantage in speculating along these lines. Stilboestrol, hexoestrol, and dienoestrol are used in enormous quantities all over the world, mainly in the treatment of menopausal disturbances and the termination of lactation. The quite unforeseen use in the treatment of carcinoma of the prostate may prove to be the opening of a new and more hopeful chapter in the control of malignancy.