Joseph A. Sorg, A. Sonenshein
Dec 5, 2008
Citations
4
Influential Citations
189
Citations
Quality indicators
Journal
Journal of Bacteriology
Abstract
ABSTRACT Some cholate derivatives that are normal components of bile can act with glycine to induce the germination of Clostridium difficile spores, but at least one bile component, chenodeoxycholate, does not induce germination. Here we show that chenodeoxycholate inhibits the germination of C. difficile spores in response to cholate and taurocholate.