B. Fu, D. Du, Qing Xia
Feb 1, 2004
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Influential Citations
5
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Journal
Synthesis
Abstract
A series of novel C 2 -symmetric bis(thiazoline) ligands with dibenzo[a,c]cycloheptadiene backbone as the substituent on the thiazoline ring were synthesized using the simple reagent phosphorus pentasulfide, and their application in catalytic allylic alkylation was investigated by comparison with the corresponding bis(oxazolines). Palladium-bis(oxazoline) complexes furnished good enantioselectivity (up to 87% ee), while bis(thiazolines) only gave up to moderate enantioselectivity (56% ee) with CH 2 Cl 2 as solvent. Preliminary explanation of the catalysis mechanism is given for the difference of two types of Pd(0)-ligand complexes.