M. Ishizaki, O. Hoshino
Jul 1, 1994
Citations
0
Influential Citations
7
Citations
Journal
Chemistry Letters
Abstract
Optically active 1-(2-, 3-, and 4-pyridyl)propanols and 1-(3-pyridyl)ethanol were synthesized in good to high enantiomeric excesses (up to 88% e.e.) and in a short reaction time by catalyzed asymmetric addition of dialkylzinc to pyridine-2-, 3- and 4- carboxaldehydes and 6-bromopyridine-2-carboxaldehyde in the presence of tridentate chiral 2-[2,2-dimethyl-1-(2-pyridyl)propoxy]-1,1-diarylethanols.