T. Fujisawa*, K. Tajima, T. Sato
Oct 5, 1984
Citations
0
Influential Citations
12
Citations
Journal
Chemistry Letters
Abstract
The ester enolate Claisen rearrangement of (R)-1-methyl-(E)-2-butenyl hydroxyacetate provides complete asymmetric transfer along with 98% erythroselectivity to give (2R,3S)-2-hydroxy-3-methyl-(E)-4-hexenoic acid. Its synthetic utility is demonstrated by the stereocontrolled synthesis of optically active pheromones.