S. M. and, S. B. Chandalia
1999
Citations
0
Influential Citations
12
Citations
Journal
Organic Process Research & Development
Abstract
An alternative manufacturing process scheme was developed for 2,6-dichlorotoluene, 2,6-dichloroaniline, and 2,6-dichlorophenol, involving oxidative chlorination after protection of the starting material in the para position followed by deprotection involving desulphonation or decarboxylation. Oxidative chlorination of 4-methylbenzenesulphonic acid, 4-methylbenzoic acid, 4-aminobenzoic acid, and 4-hydroxybenzoic acid by using HCl−H2O2, and their subsequent desulphonation or decarboxylation, gave a 60−75% yield of the desired product.