K. Rubina, I. Iovel', Y. Gol'dberg
Apr 1, 1989
Citations
0
Influential Citations
2
Citations
Journal
Chemistry of Heterocyclic Compounds
Abstract
When methylazines (2-, 3-, and 4-methylpyridines, methylpyrazine) are treated with N-chlorosuccinimide they undergo successive chlorination of the methyl group to give 2-chloromethylpyridine, 2-dichloromethylpyridine, and dichloromethylpyrazine in preparative yields. 3-Dichloromethylpyridine was synthesized from pyridine-3-aldehyde and PC15. The primary chlorination products of 4-methylthiazole are 4-methyl-5-chlorothiazole and 5-chloro-4-chloromethylthiazole.