Jordi Eras, Jonh Jairo Méndez, Mercè Balcells
2002
Citations
0
Influential Citations
24
Citations
Journal
The Journal of organic chemistry
Abstract
A new methodology for obtaining chlorohydrin esters using a one-pot esterification-chlorination reaction, in which one of the reagents, chlorotrimethylsilane, acts as solvent, is described. The reaction is stereospecific and its regioselectivity depends on the number of carbons between the hydroxyl groups present in the starting material. A mechanism is proposed.