G. Prakash, T. Mathew, Chiradeep Panja
Jun 22, 2007
Citations
1
Influential Citations
70
Citations
Quality indicators
Journal
The Journal of organic chemistry
Abstract
A mixture of nitrate salt and chlorotrimethylsilane is found to be a mild and efficient reagent for the direct oxidative conversion of thiols (1) and disulfides (2) to the corresponding sulfonyl chlorides (3) in excellent yields through oxidative chlorination. Sulfides and sulfoxides were also found to undergo oxidation to sulfones under similar reaction conditions. In most cases these reactions are highly selective, simple, and clean, affording products in high yield and purity.