C. Agami*, F. Couty, G. Evano
Oct 21, 2000
Citations
0
Influential Citations
14
Citations
Journal
Tetrahedron Letters
Abstract
Stereodefined allylic alcohols prepared from a (R)-phenylglycinol-derived Weinreb amide undergo a Claisen rearrangement with a high level of stereocontrol. The produced N-Boc-2-alcenyloxazolidines can be either hydrolyzed to afford enantiomerically enriched enals or further epoxidized using a two-step sequence. The resulting epoxyoxazolidines can then be transformed into trisubstituted cyclopropanes.