Qing-zhi Zhang, A. Kulczyńska, D. Webb
Jan 22, 2013
Citations
0
Influential Citations
10
Citations
Journal
Chemical communications
Abstract
This communication describes the synthesis of a new class of N-hydroxyguanidine (NHG) pro-drugs which release nitric oxide (NO), triggered by the action of γ-glutamyl transpeptidase (γ-GT), and have potential for the treatment of acute renal injury/failure (ARI/ARF).