J. Ichikawa, T. Mori, Y. Iwai
Sep 18, 2004
Citations
0
Influential Citations
28
Citations
Journal
Chemistry Letters
Abstract
Disfavored 5-endo-trig cyclizations were achieved in 1-trifluoromethylvinyl compounds with a sulfonamido group via (i) intramolecular SN2' reaction with loss of a fluoride ion or (ii) intramolecular addition to the vinylic group. These reactions provided indoline and pyrrolidine derivatives bearing fluorinated one-carbon units such as difluoromethylene and trifluoromethyl groups.