C. Parnell, K. Vollhardt
1985
Citations
0
Influential Citations
42
Citations
Journal
Tetrahedron
Abstract
Abstract Cocyclization of bis(trimethylsilyl)- and bis(trimethylstannyl)di-2-propynyl ether with acetonitrile provides a synthetic entry into 1,3-dihydro-6-methyl-4,7-bis(trimethylsilyl)- and bis(trimethylstannyl)-furo[3,4- c ]pyridines. Regioselective electrophilic substitution of the respective silyl or stannyl groups allows for a regiocontrolled construction of tetrasubstituted pyridines. This method has been applied to a total synthesis of vitamin B 6 .