Daniel P. Bassler, Amir Y. Alwali, Laura E Spence
Mar 15, 2015
Citations
0
Influential Citations
15
Citations
Journal
Journal of Organometallic Chemistry
Abstract
Abstract The synthesis of α-arylated and alkenylated piperidine and azepane derivatives has been accomplished through cross-coupling of α-bromo eneformamides or enecarbamates with feedstock organic halides such as aryl and vinyl bromides, under cobalt catalysis. The coupling products, which themselves are synthetic intermediates for accessing other functionalized piperidines and azepanes are obtained in good to excellent yields.