N. Muniraj, K. R. Prabhu
Jan 28, 2019
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0
Influential Citations
57
Citations
Journal
Organic letters
Abstract
A Co(III)-catalyzed novel [4 + 2] annulation of N-chlorobenzamides with maleimides has been reported. Mostly, maleimides are known to furnish the Michael-type or 1,1-type cyclized products while treating with amides. In this reaction, maleimides furnished [4 + 2] annulated products in good yields at room temperature while being treated with the internal oxidizing N-chlorobenzamide as a directing group. The developed methodology is compatible with a variety of functional groups. The [4 + 2] annulated products obtained are featured in some biologically active molecules.