M. Gangoda, R. Gilpin
1988
Citations
0
Influential Citations
5
Citations
Journal
Journal of Chromatography A
Abstract
Abstract The use of the non-ionic surfactant, N-(2-hydroxy-ethoxyethyl)-2,2,3,3,4,4,4-heptafluorbutanamide as a liquid chromatographic mobile phase modifier has been studied. Comparisons between this fluorinated compound and two similar hydrocarbon surfactants, N-(2-hydroxyethoxyethyl)-hexanamide and N-(2-hydroxyethoxyethyl)-heptanamide, have been made. Although surface tension data were similar for all three surfactants, the fluoroalkyl compound was found to have a larger influence on retention. Likewise, the positional isomers of cresol and toluidine were resolvable using the fluorinated surfactant and were not with the equivalent alkyl surfactant with a similar hydrophilic-lipophilic balance.