Kang Zhong-lian
2015
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0
Influential Citations
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Citations
Quality indicators
Journal
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
Abstract
Objective To compare the application effect in the emergent treatment of elderly patients with acute myocardial infarction between isoamyl nitrate and nitroglycerin. Methods From June 2009 to December 2013, a total of 60 elderly patients with acute myocardial infarction were selected in the Department of Cardiology,the Third People' s Hospital of Yibin,and they were divided into A group( n = 27) and B group( n = 33) according to therapeutic methods. Patients of A group were given isoamyl nitrate, while patients of B group were given nitroglycerin, both groups continuously treated for 3weeks. Clinical effect,serum levels of CK,CK-MB and BNP before treatment and after 24 hours of treatment were compared between the two groups,and the incidence of adverse reactions during treatment was observed. Results The clinical effect of A group was statistically significantly better than that of B group( Z =- 2. 143,P = 0. 032). No statistically significant differences of serum level of CK,CK-MB or BNP was found between the two groups before treatment( P 0. 05),while serum levels of CK,CK-MB and BNP of A group were statistically significantly lower than those of B group after 24 hours of treatment( P 0. 05). The incidence of adverse reactions of A group was 18. 5%, that of B group was 30. 3%, the difference was not statistically significantly different( P 0. 05). Conclusion Isoamyl nitrate has better application effect in the emergent treatment of elderly patients with acute myocardial infarction than nitroglycerin,can effectively improve the cardiac function,has relatively high safety.