M. Caira
Oct 1, 1991
Citations
1
Influential Citations
18
Citations
Journal
Journal of Crystallographic and Spectroscopic Research
Abstract
The crystal and molecular structures of the 1∶1 complexes sulfadimidine·2-aminobenzoic acid (I) and sulfadimidine·4-aminobenzoic acid (II) are described and compared with known structures containing sulfadimidine. In each complex, molecular association is maintained by one N-H⋯O hydrogen bond, and one O-H⋯N hydrogen bond involving the imino N and one pyrimidinyl N atom of sulfadimidine and the two carboxyl O atoms of the aromatic acid. The conformation of the sulfadimidine molecule inII is unusual for anN1-substituted arylsulfonamide. Molecular dimensions for the complexed aminobenzoic acids are virtually the same as those reported for the free acids. Partial correlation between carboxylic acid strengths and the hydrogen bonded N⋯O distances is observed in sulfadimidine complexes of this type.