C. Supuran
1996
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Journal
Main Group Metal Chemistry
Abstract
Complexes of chlorothiazide (6-chloro-7-sulfamoyl-1.2.4-benzothiadiazine-1,1-dioxide) a widely used diuretic and antihypertensive agent with divalent metal ions (Be(ll); Mg(II); Zn(II); Cd(II): Hg(ll) and Pb(II) ) were prepared and characterized by elemental analysis, spectroscopic, thermogravimetric, and conductimetric measurements. The complexes were tested as inhibitors of the enzyme carbonic anhydrase (CA).