Yan Xiu-zhen, Kuo Yao-Haur, Lee Tsong-Jyh
1989
Citations
1
Influential Citations
15
Citations
Quality indicators
Journal
Phytochemistry
Abstract
Abstract Two cytotoxic compounds, isodiospyrin and β-amyrin, in addition to an inactive triterpene, olean-12-en-3-one, have been isolated from Diospyros morrisiana. The cytotoxic activity of isodiospyrin, which has ed 50 values of 4.9 and 0.59 μg/ml, respectively, against HCT-8 colon tumour and P-388 lymphocytic leukemia, was demonstrated for the first time. Results of single-crystal X-ray analyses of β-amyrin acetate and olean-12-en-3-one are also reported.