A. Andreani, D. Bonazzi, M. Rambaldi
Nov 1, 1980
Citations
0
Influential Citations
1
Citations
Journal
Il Farmaco; edizione scientifica
Abstract
6-Substituted 5-hydroxymethylimidazo[2.1-b]thiazoles and 2,3-dihydro-5-hydroxymethylimidazo[2,1-b]thiazoles (VII - XII) were prepared by reducing the corresponding aldehydes (I - VI) with NaBH4. Among the acetic (VII a - XII a), methylcarbamic (VII b - XII b) and ethylcarbamic esters (VII c - XII c), compound (VII a) was active in a preliminary P388 leukemia test.