Rubina Shaheen, Dr S. H. Rizwan
2020
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Quality indicators
Journal
International Journal of PharmTech Research
Abstract
Emtricitabine is a nucleoside reverse transcriptase inhibitor for the prevention of HIV infection. This drug's, clinical and pharmaceutical analysis requires effective analytical procedures and stability studies for quality control and pharmacodynamics and pharmacokinetic studies. A comprehensive literature survey published in various journals related to analytical and pharmaceutical chemistry was conducted and instrumental analytical methods were developed and used in bulk drugs and pharmaceutical dosage form as single and combined with other drugs. This review will critically examine UV spectroscopy analytical methods (simultaneous equation method, derivative spectrophotometric method, absorption ratio and Qbased method), High-performance liquid chromatography (HPLC), High-performance thinlayer chromatography (HPTLC), Liquid chromatography coupled with tandem mass spectrometry (LC-MS).