H. Rosenkranz, G. Klopman
Mar 1, 1987
Citations
0
Influential Citations
9
Citations
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Abstract
N-Nitrosothiazolidine 4-carboxylic acid (NTCA), a sulphur-containing nitrosamine present in human urine, was predicted to be non-carcinogenic by CASE, the newly developed Computer Automated Structure Evaluating system. On the other hand, N-nitrosothiazolidine (NTHZ), a nitrosamine present in food products, was predicted to be carcinogenic. The putative non-carcinogenic NTCA may be metabolized to NTHZ, a predicted carcinogen.