Tang Ming-yue
2007
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Quality indicators
Journal
Journal of Harbin Medical University
Abstract
Objective To determine the permeability of prolonium iodide through blood-ocular barrier.Methods The adult rabbits were divided into 4 groups randomly.In the group 1,every rabbit was injected 25mg/kg prolonium iodide with intramuscular injection;In the group 2,every rabbit was injected 0.4mL prolonium iodide with subcon junctive injection;In the group 3,every rabbit was injected 0.9% NaCl with intramuscular;In the group 4,every rabbit was injected 0.4mL 0.9 NaCl with subcon junctive.After injecting the prolonium iodide concentration was detected in different time by means of arsenic and cerium calalysis spectophotometry.Results The concetration in aqueous humor in the intramuscular and subcon junctive injection groups were higher then that in other groups.Conclusion Prolonium iodide could enter aqueous humor of rabbit through blood-ocular barrier.