T. Coursindel, Jean Martínez, I. Parrot
Aug 1, 2011
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0
Influential Citations
4
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Journal
European Journal of Organic Chemistry
Abstract
Starting from Boc-activated diketopiperazines, original bicyclic derivatives of trans- and cis-2-aminocyclopentanecarboxylic acid were prepared by using two stereospecific tandem reactions. One of them is a tandem transannular rearrangement of activated lactams/alkylation process leading to the stereoselective synthesis of suitably chiral pyrrolidine-2,4-diones, allowing subsequent Michael-initiated ring closure, a simple and concise route to original multifunctionalized alicyclic β-amino esters.