Hongjuan Hu, T. J. Harrison, P. D. Wilson
Apr 24, 2004
Citations
1
Influential Citations
53
Citations
Journal
The Journal of organic chemistry
Abstract
A modular and concise total synthesis of (+/-)-daurichromenic acid has been accomplished in four steps from ethyl acetoacetate, ethyl crotonate, and trans,trans-farnesal. A series of analogues of this natural product, which has potent anti-HIV activity, were also prepared from ethyl or methyl acetoacetate and a series of readily available alpha,beta-unsaturated esters and aldehydes.