V. Soloshonok, H. Ohkura, M. Yasumoto
2006
Citations
0
Influential Citations
7
Citations
Journal
Mendeleev Communications
Abstract
The reaction of 1,1,1,5,5,5-hexafluoropentane-2,4-dione with ( R )-phenylglycinol proceeds via the intermediate formation of ( R ,4 E ,6 Z )-5,7-bis(trifluoromethyl)-2,3-dihydro-3-phenyl-1,4-oxazepine, which further undergoes a base-catalysed 1,3-proton shift followed by [1,2] Wittig rearrangement giving rise to 2,4-bis(trifluoromethyl)-6-phenylpyridine.