J. Pavlik, Theppawut I Ayudhya, S. Tantayanon
Sep 1, 2002
Citations
0
Influential Citations
12
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
In contrast to previous reports, 4-ethoxy-1,1,1-trifluoro-3-buten-2-one (1) was observed to react with methylhydrazine (2) in refluxing ethanol to yield 1-methyl-3-(trifluoromethyl)pyrazole (6) and 4,5-dihydro-1-methyl-5-(trifluoromethyl)pyrazol-5-ol (4). The later compound undergoes acid catalyzed dehydration to 1-methyl-5-(trifluoromethyl)pyrazole (3).