J. Kamerling, M. Durán, L. Bruinvis
Nov 10, 1982
Citations
0
Influential Citations
7
Citations
Quality indicators
Journal
Clinica chimica acta; international journal of clinical chemistry
Abstract
Abstract The absolute configuration of urinary 5-hydroxyhexanoic acid was determined by means of capillary gas-liquid chromatography of the O- D -2-phenylpropionylated methyl ester derivatives on SE-30 as stationary phase. In three patients with non-ketotic dicarboxylic aciduria and one patient on a diet containing excessive amounts of medium-chain triglycerides, ∼ 70% of the L -isomer and ∼ 30% of the D -isomer were found. On the basis of these results it is concluded that 5-hydroxyhexanoic acid is a ‘normal’ degradation product of fatty acids.