C. Foces-Foces, F. H. Cano, M. Bernabé
Dec 15, 1984
Citations
0
Influential Citations
20
Citations
Journal
Carbohydrate Research
Abstract
Abstract The crystal and molecular structure of 2-phenyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α- d -glucopyrano)-[2,1-d]-2-oxazoline (2) has been determined. The compound crystallises in the space group P21212 with lattice constants 13.4160(3), 37.4931(14), and 7.7886(1) A, and Z = 8. Direct methods were used in the solution. Least squares refined the model with 3213 observed (with 2σ) reflections down to an R value of 0.053 and Rω 0.060. The pyranoid rings have slightly different conformations, being between skew oS2 and diplanar D0,4. The conformations of 2 and 2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α- d -glucopyrano)-[2,1-d]-2-oxazoline in solution have also been investigated by 1H-n.m.r. spectroscopy. The computed best values of the coupling constants have been used with several Karplus-type equations and have been interpreted in terms of a skew oS2 major conformation of the pyranoid ring in each compound.