S. Davies, H. Rodríguez‐Solla, J. Tamayo
Oct 28, 2004
Citations
0
Influential Citations
14
Citations
Journal
Chemical communications
Abstract
A highly diastereoselective conjugate reduction using SmI2 and D2O has been demonstrated on a homochiral benzylidene diketopiperazine template, giving methyl (2S,3R)-N-acetyl-2-amino-2,3-dideuterio-3-phenylpropionate in 93% de and 90% ee after deprotection, hydrolysis and N-acetylation.