S. Yoo, Ju Sun Kim, S. Kang
Dec 1, 2002
Citations
1
Influential Citations
60
Citations
Quality indicators
Journal
Archives of Pharmacal Research
Abstract
Four flavonoid glycosides, flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplex-oside (10), the steroids β-sitosterol (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) andmyo-inositol (14) have been isolated fromEuodia daniellii. The structures of these compounds were established from spectral data. Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an IC50 value of 6.2 μg/ml. Fla-vonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.