Yu‐Hua Tian, Hyun-chul Kim, J. Cui
2005
Citations
2
Influential Citations
40
Citations
Quality indicators
Journal
Archives of Pharmacal Research
Abstract
Phytochemical investigation of the MeOH extract of the root barks ofCudrania tricuspidata Bureau (Moraceae), as guided by hepatoprotective activityin vitro, furnished four isoprenylated xanthones, cudratricusxanthone A (1), cudraxanthone L (2), cudratricusxanthone E (3), and macluraxanthone B (4). All of these compounds showed the significant hepatoprotective effect on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. Compounds1, 2, and4 also exhibited the significant hepatoprotective effect on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells.