Ye Si-neng
2004
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Quality indicators
Journal
Medical Journal of Chinese People Heacth
Abstract
Object: To evaluate the clinical curative effects and safety of national Loxpine succinate in the treatment to Schizophrenia . Method:Nine phsycial hospitals took up the clinical comparative analysis . The patients with schizophrenia were randomly assigned into the treatment groups up Loxapine Succinate or Chlorpromazine Hydrochloride for 8 weeks PRS and CGI scales were used the measure their clinical efficacy and side effects between Loxapine and Chlorpromazine group. Result: In efficacy two groups have no significant difference.They have the same response rate of over 90%.While an obviously effective rates of about 60%.Loxapine which has a rapid onset of effect is superior to chlorpromazine in prime curative,the two groups have no significant difference in the main side effective rates prime curative,the two groups have no significant difference in the main side effects such as A kathisia and Tremor,they can release witE the use of Artaze and/or inderal . Conclusion: Loxapine is an effective antipsychotic drug,It can be used in the clinical curative as a anti-psychosis drug for its rapid curative effects and security.