Beedimane Narayana Manjunath, Neeraj P. Sane, Indrapal Singh Aidhen
Jun 1, 2006
Citations
0
Influential Citations
22
Citations
Journal
European Journal of Organic Chemistry
Abstract
A new reagent for the synthesis of the α,β-unsaturated N-methoxy-N-methyl-amide structural unit has been developed. 2-(Benzo[d]thiazol-2-ylsulfonyl)-N-methoxy-N-methylacetamide, a crystalline solid with an indefinite shelf life that can be easily prepared in two convenient steps from 2-chloro-N-methoxy-N-methylacetamide, reacted with a variety of aldehydes under Julia conditions to furnish the α,β-unsaturated N-methoxy-N-methyl-amide functionality. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006)