R. Carr, Karl M. Cable, Guy N. Wells
Sep 1, 1994
Citations
0
Influential Citations
14
Citations
Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
A variety of [13C]-labelled aromatic nitriles have been prepared in good yield from iodoaromatic substrates. Cyanation was achieved by reaction of aryl iodides with a mixture of potassium [13C]-cyanide and copper (I) iodide in an aprotic solvent at high temperature. The use of pre-prepared carbon-labelled copper (I) cyanide was therefore obviated.