Y. Matsumura, M. Inoue, Yasuharu Nakamura
Jun 12, 2000
Citations
0
Influential Citations
21
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 2,3-Didehydro-1,2-bis(methoxycarbonyl)-6-methoxypiperidine ( 4 ), prepared from l -lysine by using electrochemical oxidation, was cyclopropanated with high diastereoselectivity (96.6% de), and the cyclopropanated product was transformed to optically active 2,3-methanopipecolic acid ( 1 ). In this transformation, the 6-methoxy group of 4 was found to be an effective chiral auxiliary.