Kazuhito Hioki, Yumiko Takechi, Noriyo Kimura
Dec 1, 2008
Citations
0
Influential Citations
6
Citations
Journal
Chemical & pharmaceutical bulletin
Abstract
Simple one-pot methods for preparation of 2-oxazolines have been developed using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride (DMT-MM). Treatment of a mixture of carboxylic acids and 2-haloethylammonium salts with DMT-MM in methanol followed by refluxing in the presence of KOH gives oxazolines.