J. Crosby, M. C. Mckie, R. Paton
Oct 11, 2000
Citations
0
Influential Citations
8
Citations
Journal
Arkivoc
Abstract
Isothiazole-3- and 4-carboxylate esters are readily prepared by 1,3-dipolar cycloaddition of nitrile sulfides, generated by thermal decarboxylation of the corresponding 1,3,4- oxathiazol-2-ones, to acrylate, fumarate and maleate esters, followed by phase-transfer- mediated hypochlorite oxidation of the resulting 2-isothiazoline cycloadducts.