Carlos Jonnatan Pimentel Barros, Zilyane Cardoso de Souza, J. C. R. Freitas
Mar 1, 2014
Citations
0
Influential Citations
5
Citations
Journal
Journal of The Chilean Chemical Society
Abstract
The synthesis of 3-aryl-5-pentyl-1,2,4-oxadiazoles from carboxylic acid esters and arylamidoximes in the presence of potassium carbonate is described. The reaction was carried out in a microwave oven without any solvent in much shorter time and in good yields. The structures of the synthesized compounds were elucidated using IR, 1H and 13C NMR spectroscopy and elemental analysis and their antiproliferative activities was evaluated against three different human cell lines.