C. Espinosa-Bustos, Alondra Villegas, C. Salas
May 7, 2017
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Journal
Arkivoc
Abstract
A convenient and simple synthesis of novel N-arylated 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine using several aryl boronic acids and copper (II) acetate is described. The yields obtained for all derivatives are in the range of 45-70 % and this synthetic approach is extensible to other heterocycles such as 1H-indazoles.