M. Shabbir, Z. Akhter, Iqbal Ahmad
Mar 9, 2017
Citations
0
Influential Citations
30
Citations
Journal
Polyhedron
Abstract
Abstract Four novel copper complexes bis((E)-2-((4-phenoxyphenylimino)methyl)phenolate) copper(II) (CuL1), bis((E)-2-((4-(4-biphenyloxy)phenylimino)methyl)phenolate) copper(II) (CuL2), bis((E)-2-((4-(naphthalen-1-yloxy)phenylimino)methyl)phenolate) copper(II) (CuL3) and bis((E)-2-((4-(2-naphthoxy)phenylimino)methyl)phenolate) copper(II) (CuL4) have been synthesized and characterized by FTIR spectroscopy, elemental analysis and electro-analytical techniques. Single crystal X-ray diffraction analysis of complex (CuL1) revealed that the compound crystallizes in the orthorhombic crystal system. The absolute structure has been determined from the diffraction data. The molecule lies on a 2-fold axis with geometry intermediate between square planar and tetrahedral. In the complexes the ligands are bidentate, coordinating through phenolate oxygen and azomethine nitrogen to the copper ions. The biological studies (cytotoxic and antitumor) have revealed their bioactive nature. Results of brine shrimp cytotoxicity indicated their LD50 values