Zhi-Qiang Zhang, Tao Chen, Fu‐Min Zhang
Feb 16, 2017
Citations
0
Influential Citations
47
Citations
Journal
Organic letters
Abstract
An efficient and direct Cu-assisted nitrating approach to create synthetically valuable and challenging tertiary α-nitro-α-substituted moieties has been developed using ceric ammonium nitrate as a nitrating reagent, oxidant, and Lewis acid. Notably, the commonly used clinical drug ketamine was smoothly synthesized in four steps.