Shaoqun Zhu, Ying-min Pan, Yue Sun
Mar 8, 2022
Citations
0
Influential Citations
6
Citations
Journal
The Journal of organic chemistry
Abstract
A copper-catalyzed bromo-cyanomethylative cyclization of 1,6-enynes is demonstrated. The treatment of 2-bromoacetonitrile with CuI enables the alkyl radical generation and triggers the radical addition/cyclization/bromination sequence, giving various vinyl C-Br bonds containing functionalized heterocycles in good yields.