Z. Liang, Fei Wang, Pinhong Chen
Apr 24, 2015
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Influential Citations
91
Citations
Quality indicators
Journal
Organic letters
Abstract
A highly selective and efficient approach for the direct trifluoromethylthiocyanation of alkenes has been developed using trimethylsilyl isothiocyanate (TMSNCS) as the thiocyanating agent and Togni reagent as the CF3 source in the presence of copper(I) catalyst. Both activated and unactivated alkenes work well to deliver various CF3-containing thiocyanates.