Z. Zhou, Cheng-Kun Li, Shaofang Zhou
May 11, 2017
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron
Abstract
Abstract Copper-catalyzed radical methylation of 1,3-diketones with tert-butyl peroxybenzoate in air is described, providing a general pathway to α-methyl 1,3-diketones in moderate to good yields. This protocol has been scaled up to 50 g, and one of the synthesized products can be used in the synthesis of medicine, Rosuvastatin.