Shiv Dhiman, H. Saini, N. Nandwana
Mar 1, 2016
Citations
1
Influential Citations
15
Citations
Journal
RSC Advances
Abstract
A novel regioselective synthesis of 2-aminoquinolines and 2-arylquinoline-3-carbonitriles is described via copper-mediated tandem reaction. Formation of substituted quinolines involves Knoevenagel condensation of ortho-bromobenzaldehyde with active methylene nitriles followed by copper-catalyzed reductive amination and intramolecular cyclization.