Yun Zhang, H. Du, Mingxiang Zhu
Mar 1, 2017
Citations
0
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
An efficient Cu-catalyzed stereoselective trifluoroethylation through the decarboxylative cross-coupling of cinnamic acid derivatives with CF3CH2I is described. The ready availability of the starting materials, the high level of functional group tolerance, and excellent E selectivity make this protocol a safe and operationally convenient strategy for the efficient synthesis of trifluoroethyl derivatives.