K. Fuchibe, Tatsuya Aono, Ji Hu
Aug 30, 2016
Citations
0
Influential Citations
22
Citations
Journal
Organic letters
Abstract
Silyl dienol ethers readily underwent copper(I)-catalyzed [4 + 1] cycloaddition with sodium bromodifluoroacetate to afford 4,4-difluorocyclopent-1-en-1-yl silyl ethers. On the basis of high-resolution mass spectroscopy analysis, annulation presumably proceeded via a copper(I) difluorocarbene complex, which represents an unprecedented example of [4 + 1] cycloadditions promoted by a transition metal difluorocarbene complex.